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Research Staff

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Helen N. Jones, PhD.

Helen N. Jones, PhD

Title

Research Associate

Email

helen.jones@cchmc.org

Phone

513-636-7861

Fax

513-636-2735

Credentials

PhD: Rowett Research Institute, University of Aberdeen, Scotland. 2005
BS: Biochemistry, University of St. Andrews, Scotland. 2000

Position History

  • Postdoctoral Research Fellow, OB/GYN, University of Cincinnati, OH. 2006-2009
  • Postdoctoral Research Scientist, Rowett Research Institute, University of Aberdeen, Scotland, 2005-2006
  •  Research Assistant, COPD, Bayer, England. 2000-2002

Awards and Honors

  • Perinatal Symposium New Investigator Award 2008
  • International Federation of Placenta Associations NIH New Investigator Awards 2006, 2007
  • European Nutrition Leadership Programme (ENLP) 2005
  • International Federation of Placenta Associations Y W (Charlie) Loke Young Investigator Awards 2003, 2004, 2005
  • Physiological Society Affiliate member travel grant 2004
  • Society for Reproduction and Fertility travel grant 2004
  • Royal Society Partnership Grant 2003-2004

Research

Regulation of placental growth and function; regulation of mechanisms of placental nutrient transfer and consequences for fetal growth

Publications, Most Recent

Jones HN, Jansson T, Powell TL. IL-6 stimulates System A amino acid transporter activity in trophoblast cells through STAT3 and increased expression of SNAT2.Am J Physiol Cell Physiol. doi:10.1152/ajpcell.00195.2009

Jones HN, Woollett LA, Barbour N, Prasad PD, Powell TL, Jansson T. High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice.FASEB J. 2009 Jan;23(1):271-8

McArdle HJ, Andersen HS, Jones H, Gambling L. Copper and iron transport across the placenta: regulation and interactions.J Neuroendocrinol. 2008 Apr;20(4):427-31.

HN Jones, TL Powell, T Jansson (2007). Regulation of Placental Nutrient Transport – A Review. Placenta, 28. 763- 774.

HN Jones, CJ Ashworth, KR Page & HJ McArdle (2006). Expression and adaptive regulation of amino acid transport system A in a placental cell line under amino acid restriction.Reproduction. 131:951-60.

HN Jones, CJ Ashworth, KR Page & HJ McArdle (2006). Cortisol stimulates System A amino acid transport and SNAT2 expression in a human placental cell line (BeWo). Am. J. Physiol Endocrinolgy and Metabolism. 291(3):E596-603.

McArdle HJ, Andersen,HS, Jones,H and Gambling,L. Fetal Programming: Causes and Consequences as Revealed by Studies of Dietary Manipulation in Rats – A Review.Placenta, 2006;27:56-60.

Ferguson-Smith AC, Moore T, Detmar J, Lewis A, Hemberger M, Jammes H, Kelsey G, Roberts CT, Jones H, Constancia M. Epigenetics and imprinting of the trophoblast -- a workshop report.Placenta. 2006 Apr;27 Suppl A:S122-6

Presentations, Most Recent

Jones HN, Jansson T, Powell TL. Differential effects of globular and full length Adiponectin on placental System A amino acid transporter expression and activity. Presented at the Society for Gynecologic Investigation (SGI) March 2009, Glasgow, UK.

Jones HN, Barbour N, Woollet LA, Powell TL, Jansson T. Development of a mouse model of obesity in pregnancy. Presented at SGI March 2008, San Diego, CA.

Jones HN, Barbour N, Woollet LA, Powell TL, Jansson. T. Increasing maternal dietary fat content results in fetal overgrowth in mice. Presented at the Aspen Perinatal Symposium August 2007, Aspen CO.

Jones HN, Powell TL, Jansson T. Regulation of placental amino acid transport by cytokines/adipokines. Presented at the International Federation of Placental Associations (IFPA) August 2007, Kingston, Canada.

Jones HN, Campbell G, Mayer C-D, McArdle HJ Regulation of Gene Expression by micronutrient deficiencies in a placental model. Presented at the IFPA September 2006, Kobe, Japan

Professional Organization Memberships

  • American Physiological Society
  • International Federation of Placental Associations
  • Placental Association of the Americas
  • Society for Gynelogical Investigation

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